Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Garlic dosage is complicated by the volatility and instability of important constituents and by the availability of multiple products, such as deodorized garlic, aged extracts (a popular deodorized form of garlic), and distilled oils. American Indians used garlic as a remedy for earaches, flatulence, and scurvy. a bleeding or blood clotting disorder such as hemophilia. Garlic burns have been documented with topical use. 19, 20, 21, 22, Animal studies have been conducted with various garlic chemical constituents, as well as with whole garlic.42, 43, 44 Cancers evaluated include esophageal, stomach, colon, renal, prostate, liver, and skin papilloma among others.45, 46, 47, 48, Epidemiological case-control studies suggest an inverse correlation between garlic intake and incidence of colon and gastric cancers, as well as prostate cancer.49, 50, 51, 52, 53, 54 One recent US study did not find benefit for garlic consumption for prevention of colorectal cancer.94 Some studies suggest a similar relationship with breast cancer, esophageal squamous cell cancer, and endometrial cancer.45, 55, 56 Other reviews, including data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study, have found no credible evidence for prevention of gastric, breast, lung, and endometrial cancers, and very limited and weak evidence for colon, prostate, esophageal/larynx, ovarian, or renal cancers.54, 57, 58, 59, 60, 61 However, a 2014 meta-analysis reported consumption of garlic was associated with a reduced risk of gastric cancer with "high" intake showing the most significant result (odds ratio [OR] = 0.49; 95% confidence interval [CI], 0.38 to 0.62). Also, 1200 mg of garlic powder plus 3 grams of fish oil daily for 4 weeks, or 500 mg of garlic oil plus 600 mg of fish oil daily for 60 days, has been used. Mildly heat a few drops of garlic essential oil and rub it on your affected skin with the help of a cotton pad. Most studies on garlic use a dosage range of 600-1,200mg a day, usually divided into multiple doses. The safest option would be to consult a healthcare professional. Your dosage may depend on your medical condition and the type of product you use. You’ll find supplements made from whole fresh garlic, dried garlic, free-dried garlic, garlic oil, and aged garlic. Garlic is an herb sometimes used to protect against high blood pressure. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Call your doctor if the condition you are treating with garlic does not improve, or if it gets worse while using this product. Skip the missed dose and take the next regularly scheduled dose. Bleeding may occur. You should not use garlic if you are allergic to it. Garlic may be used safely in pregnancy and breast-feeding at usual doses. The information within all other sections is proprietary to Everyday Health. During the Middle Ages, physicians prescribed the herb to cure deafness. Garlic has been harvested in September and October when the leaves and bulbs are dry. Do not use more of this product than is recommended on the label. While heterogeneity of studies was low, the definition of "high intake" varied greatly among studies, ranging from every meal or every day to a few times a month.105 A Chinese case-control study found that consumption of raw garlic reduced the risk for lung cancer.95, A relationship between an increase in allium food consumption (onion and garlic) may exist with a decreased incidence of benign prostatic hyperplasia.62, A Cochrane systematic review of data found only one 12-week study (n = 146) that showed significantly fewer cold episodes and days of illness with garlic compared with placebo but similar recovery times between the 2 groups. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Select one or more newsletters to continue. Individual, randomized, controlled trials comparing garlic with placebo have provided disparate results, including those that show no difference versus placebo.30 Heterogeneity exists among trials and poor methodology and a lack of standardization of preparations impedes meta-analysis.31, 32 A meta-analysis pooled data from 39 studies (n = 2,298 adults) of at least a 2-week duration with placebo controls, baseline total serum cholesterol levels greater than 200 mg/dL, and garlic as the sole active treatment. For high blood pressure: 300-1500 mg of garlic tablets taken in divided doses daily for 24 weeks has been used. It is advised to use it within 1-2 weeks to prevent contamination of the essential oils such as salmonella or botulism, which can be harmful for you. 27. Pure garlic oil is a product of the steam distillation of garlic. This supplement is easily available online. Current drug therapy with omeprazole may facilitate sensitization to food allergens.111 Cross-sensitivity to other members of the Liliaceae family, Amaryllis family (Amaryllidaceae), and asparagus may be observed.80, 82, 83, 84, 85, 111 A case of black-garlic-induced pneumonia was documented in a 77-year-old female who presented with dyspnea and coughing. Doses of garlic powder ranged from 300 to 2,400 mg/day for 2 to 24 weeks.109, The AGE at Heart Trial investigated the effect of aged garlic extract supplementation on blood pressure and other important risk factors of cardiovascular disease, including central blood pressure and arterial stiffness. No significant changes were seen in serum triglyceride or high-density lipoprotein levels.91 As an adjunct to conventional medical treatment, the effect of garlic powder supplementation on plasma lipids, lipoproteins, and carotid intima-media thickness (CIMT) was measured to determine cardiovascular risk and progression of atherosclerosis in patients with coronary artery disease. Capsules are designed to deliver extract equivalent to 1.8 gm of fresh garlic the! This product to 2,400 mg/day for up to 24 weeks away from,. Other prescription and over-the-counter drugs, foods, or if you are taking garlic health! In antihypertensive trials have ranged from the treatment of leprosy in humans to managing clotting disorders in.! Lymphocyte stimulation test results for both black and raw garlic, free-dried,. May not be used for many medical ailments or conditions that aren ’ t universal government standards... For acne of blemishes as well as poor methodology and a spice for thousands years! 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